Cholinergic drugs

Clinical uses of cholinergic drugs:

		Clinical use
Bethanicol	Choline ester. Notdestroyed by cholinesterase.	To stimulate bladder & bowels, e.g after sugery preferable to carbacol because it is more muscurinic.
Carbacol	Choline ester. Not destroyed by cholinesterase,More nicotinic.	To stimulate bladder & bowels, e.g after surgery.
Pilocarpine	Founds from pilocarpus	To lower IOP in chronic simple glucoma.
Physostigmine	Alkaloid & anti-cholinesterase obtained from seeds of physostigmin plant.	Use in atropine poisonong.
Neostigmine	Synthetic anticholinesterase	Use in Myesthenia gravis.
Endrophonium		To diagnose myesthenia gravis & to differentite a myesthenia gravies to cholinergic crisis.
OPC		Used in 1.Insecticides. 2.Homicidal poisoning.

                                                                                                                                              

Clinical uses of cholinesterase inhibitors:

1)      In diagnosis & treatment of myasthenia gravis.

2)      In treatment of glaucoma.

3)      As an antidote in atropine poisoning(physostigmine).

4)      As an antidote to competitive neuromuscular blocker(Neostigminee)

5)      Stimulate bowel & bladder after surgery.