Step
care management of severe asthma:
Step Care Management is like a staircase. We start
treatment at the appropriate step. Then we shall step up along the stairs if
asthma is not controlled or becomes more severe and shall step down when
patient's asthma is fully controlled for 3 months or more.
We have divided the asthma
management plan into five steps. At first, we should understand basic
principles of five steps. Then we can construct any step by combining available
drugs.
Basic Principles of Step Care Management
Step - I: Inflammation is so
minimal that no Preventer or anti-inflammatory medication
is required. Patient will only take Reliever drug (bronchodilator) as per need.
Onwards Step-I is kept as a part of Step II to Step V.
Step - II: For control of
inflammation, low dose Preventer (anti-inflammatory medication) is required.
Reliever drug will be used in step-II to step-V as per need, like step-I. We
can get desired low dose anti-inflammatory action by using "full dose
Cromones" or "low dose Inhaled Corticosteroids
(LDICS)" or “Leukotrienes antagonists”.
Step - III: To control
airway inflammation, high dose Preventer (anti-inflammatory medication) is
required. This means high dose inhaled Corticosteroids (HDICS). But we may give
low dose inhaled Corticosteroids (LDICS) along with Cromones or long-acting
b2-agonist (Salmeterol) inhaler or Sustained release Theophyllin (protectors)
to get the desired effect. Any of these combinations is equivalent to high dose
inhaled Corticosteroids (HDICS).
Step - IV: We have two
divisions of step-IV viz. IVA and IVB. When high dose anti-inflammatory drugs
(HDICS) are thought to be insufficient to control asthma then we use step - IVA
or IVB. Step IVA (A=alone) means addition of either Salmeterol inhaler or
Theophyllin SR alone with HDICS. Step IVB (B= both) means both Salmeterol
inhaler and Theophyllin SR will be added with HDICS.
Step - V: It is the highest
step. Oral Corticosteroid added as single morning dose
with step-IVB is known as step-V. We give this step when step IVB is thought to
be inadequate to control asthma.
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