STROKE (Neurological Disorders in Elderly)



STROKE (Neurological Disorders in Elderly)

Definition

A stroke is usually understood to be the sudden onset of neurological deficits due to local
disturbances in the blood supply to the brain, i.e. a vascular occlusion (ischemic infarct) or a
vascular disruption (hemorrhage).

Prevalence

Prevalence of stroke rapidly increases with age. Two thirds of stroke patients are found in the
over-65 age group.

Morbidity and Mortality

Stroke is the third most common cause of death and the leading cause of disability in developed
countries. In the United States, the rate of death due to stroke is 160,000 per year.2 Wagenaar
and Kwakkel reported that about 30 percent of the stroke patients died within 21 days. Of those
who survived the acute phase, 42 percent remained dependent upon other persons for their
ADLs, 24 percent were hospitalized or sent to a nursing home, 11 percent were unable to walk,
and 66 percent were unable to return to work.1 On the basis that elderly is the fastest growing
segment of world population, it may be expected that the proportion of disability will continue
to increase considerably.

Risk Factors

Age: After age 55, the risk for stroke doubles every 10 years.
Sex: Male > female for all age groups below 75 years.
Race: Afro-Caribbean > Asian > European.
Diseases: Heart diseases such as heart failure or atrial fibrillation, hypertension, diabetes,
hyperlipidemia, polycythemia.
Lifestyles: Smoking, excess alcohol consumption, obesity, diet, lack of physical activity
• Oral contraceptives.

Clinical Features

• The neurological deficit reflects the size and site of the lesion.
• At the time of onset, the level of consciousness is more depressed in patients with cerebral
hemorrhage than those with ischemic stroke.
• Acute focal stroke presents with variable symptoms. Most common is a haemiplegia with
or without the signs of focal higher cerebral dysfunction, for example aphasia. Other
symptoms are related with sensory, visual, cognitive and language deficits.
• Subarachnoid hemorrhages are not common in elderly individuals. Typically they presents
with a sudden, unusually severe headache that lasts for hours or even days, often accompanied
by vomiting.
• presents clinical features of most common forms of stroke.
• Following the onset of stroke with hemiplegia, a state of flaccidity exists from hours to
weeks or months. This is followed by the development of patterns of returning muscle
function and spasticity.

Clinical features of most common forms of stroke

Ischemia
• Middle cerebral artery Contralateral paralysis and sensory deficit
Aphasia
Homonomous hemianopsia
Hemineglect
Numbness: face, arm > leg
Apraxia
Impaired ability to judge distance
Loss of conjugate to opposite side
• Anterior cerebral artery Weakness: leg > face, arm
Numbness: leg > face, arm
Urinary incontinence
Contralateral grasp reflex, sucking reflex
Amnesia
• Vertebrobasilar artery Ataxia
Dizziness, nausea, vomiting, nystagmus
Dysmetria
Dysarthria
Dysphagia
Visual field deficits
Quadriplegia in complete basilar syndrome
Hemorrhage
• Intracerebral hemorrhage Headache
Lethargy or coma
Focal symptoms resembling ischemic stroke
• Subarachnoid hemorrhage Severe, unusual headache, often during physical exertion
There may be loss of consciousness or vomiting at onset
Nuchal rigidity takes about 6 hrs to develop
Cardiac symptoms such as chest pain, syncope, arrhythmias
Focal hemisphere signs at onset due to an associated intracerebral hematoma
Focal hemisphere signs developing after some days due to arterial vasospasm
A 3rd nerve palsy due to local pressure from an aneurysm of the posterior communicating artery

Investigations

• CT/MRI: To confirm the vascular nature of the lesion
• ECG, ultrasound scanning, Doppler ultrasound, contrast angiography: To investigate the
underlying vascular disease
• Serum glucose, complete cell and platelet blood count, cholesterol, prothrombin and partial
thromboplastin time, electrolytes: To investigate the risk factors

Evaluation and Assessment

Level of consciousness: The Glasgow Coma Scale records motor response to pain, verbal
responses to auditory as well as visual clues, and eye opening.3
Cranial nerves: Ocular movements; strength of facial muscles; labyrinthine auditory, laryngeal
and pharyngeal function, should be checked.
Sensation: Light touch, deep pressure, pain, temperature, kinesthesia, two-point
discrimination, proprioception, appreciation of texture and size, and vibration should be
assessed.
Musculoskeletal: Muscle strength as well as range of motion especially ankle dorsiflexion
and shoulder movements should be assessed thoroughly.
Movement pattern: Physical therapist should know whether the movement produced is in
normal pattern or not. Initiation pattern, sequencing and control of firing patterns, balanced
return are the indicators of controlled smooth movement pattern.
Hypertonicity: Physical therapist dealing with stroke patients should understand the difference
between ‘true spasticity’ and ‘hypertonicity’. According to Burke5 and Sheean6, ‘true
spasticity’ depends upon afferent information from feedback following movement of the
stretched muscle whereas hypertonicity which is a form of sustained efferent muscular
hyperactivity, depends upon continuous supraspinal drive to the alpha motoneurones. This
results into increased tonic muscle contraction which continues in the absence of movement.
As a consequence, hypertonicity in hemiplegia gives rise to abnormal postures such as
flexion of upper limb and extension of lower limb.
Pain: Shoulder pain is the most common pain complaint after stroke.10 It can be assessed
by using Visual Analogue Scale.
Edema: The distal parts of extremities should be observed for the presence of edema.
Communication: Physical therapist should be aware of aphasia or dysarthria as well as
alternate modes of communication such as auditory or visual deficits.
Behavior: Cognitive function and behavior problems should be noted, • Balance: The Berg Balance Assessment is easy to administer and has good reliability for
stroke patients.
Posture: Postural problems in regard with alignment or rotation, midline orientation, and the
position of extremities should be evaluated in detail.
Gait: Gait pattern is an important component of evaluation of a hemiplegic patient. Loss of
controlled planterflexion and normal combinations of movement patterns in swing and stance
phases of gait, are some of the common abnormalities. Wisconsin Gait Scale (WGS)58,59
provides the qualitative evaluation of the gait of hemiplegic patients. (Appendix- VIII)
Appliances: Use or a need to use the assistive devices, splints for positioning, orthotic
devices or wheelchair should be noted down.
ADLs:

Management

Medical management:
– The hospital stay for acute stroke is usually 2 to 4 days.
– Management starts with assessment of the “ABCs” meaning Airway, Breathing and
Circulation.
– A rapid reduction of blood pressure, especially in case of moderate elevation, should be
avoided. This is to prevent acute exacerbation of the neurological deficit.
– No treatment is recommended unless the systolic pressure is > 220 mm Hg.
– If needed, intravenous B-blockers should be administered to reduce blood pressure.
– Admission to neurointensive care unit is must in case of subarachnoid hemorrhage.
– Patients should not be allowed to take food or liquid by mouth until swallowing function
becomes normal.
– Patients should lie flat in bed so as to avoid the worsening of ischemia.
– Depending upon the stroke subtype, secondary prevention strategies should be initiated
as soon as possible. For example, aspirin and other antiplatelet drugs reduce the risk of
recurrence in noncardioembolic strokes.
Physical therapy interventions: A number of treatment approaches, ranging from neurological
exercise therapies to cognitive remediation programs for perceptual deficits, have been
developed in last four decades. The frequently applied neurological exercise therapies are
Neurodevelopmental Treatment (NDT) derived from Bobath method, Motor Relearning
Program (MRP) by Janet Carr and Roberta Shepherd, Brunnstorm’s Movement Therapy,
Proprioceptive Neuromuscular Facilitation (PNF) technique and Electromyography Feedback
Therapy (EMG). The main problem of hemiplegic patients is that of abnormal coordination of movement patterns combined with abnormal postural tonus.49 Therefore, according to Bobath, the assessment and treatment of the patient’s motor patterns is the only way of leading directly to
functional use. In addition to it, muscles are not paralyzed and deficits of muscular activity can
be remedied by their action in more normal functional patterns. Thus, basic concept of Bobath
method is a holistic approach that deals with patterns of coordination and not with problems of
muscle function. The method has undergone many changes from 1970 to 1990, but the
underlying concept has not changed. These changes can be summarized as following:50
• All static ways of treatment like ‘reflex-inhibiting postures’ have been discarded.
• A strong emphasis on movement and functional activity has been introduced.
• New ways of activating the patient through movements of the trunk have been found,
combined with the inhibition of the spastic patterns of the limbs distally by the therapist.
• As the spasticity is reduced, patient is encouraged to control movements more and more
distally, while the help of therapist is reduced.
• Treatment in supine is reduced for the patients who can sit or stand.
• More than ever before, all treatment is done in real life situations.
In 1985, Pat Davies introduced Neuro-Developmental Treatment (NDT) that is based on
Bobath’s approach; in it, the ideas of Bobath have been extended to training in functional tasks
such as grasping, standing up, climbing stairs, bouncing a ball, getting dressed, preparing
meals, washing clothes, brushing teeth and having a bath.51
Brunnstorm has described seven recovery stages in post-stroke hemiplegic patients:
Stage 1. Flaccidity is present. No movement, on either a reflex or a voluntary basis, can be
initiated.
Stage 2. Spasticity begins to develop. Flexion synergy in upper extremity and extension synergy
in lower extremity may appear as associated reactions. There are minimal voluntary movement
responses. (semivoluntary)
Stage 3. Spasticity reaches its peak. Patient is able to control the basic synergy patterns.
Stage 4. Spasticity begins to decline. Some movement combinations that do not follow the
paths of basic limb synergies are mastered.
Stage 5. Spasticity continues to decline. More difficult movement combinations are mastered
as the basic limb synergies lose their dominance.
Stage 6. As spasticity disappears, the patient becomes capable of a full spectrum of movement
patterns. Coordination approaches normalcy.
Stage 7. Normal motor function is restored.
According to Brunnstorm, these stages of recovery following a stroke bear a resemblance
to normal infantile motor development on a continuum from reflex to voluntary movement,
from gross to fine movement and from control of proximal movements to that of distal
movements. She developed the treatment strategies so as to facilitate this “natural and lawful”
process. The techniques of facilitation used by her are synergies, reflexes, associated reactions,
resistance, tapping and stretch.
With the exception of the training of basic functional activities such as grasping, sitting and
walking, training for ADL is hardly discussed by Brunnstorm.1 In addition to it, the use of
reflexes and synergistic movement in treatment is controversial and the concept of the hierarchical organization of the nervous system has been modified in neurophysiology in recent years.
However, Brunnstorm’s observations of motor recovery and motor behavior are valid and the
techniques are useful in treatment.
The Motor Relearning Program (MRP), formulated by Carr and Shepherd, is an approach
to functional training. There is a major shift, in emphasis, away from the exercise or facilitation
therapy to the relearning of motor control. In view of these applied movement scientists, the
unique contribution of physiotherapy to the rehabilitation of stroke lies potentially in the training
of motor control based on an understanding of the kinematics and kinetics of normal movement,
motor control processes and motor learning. Thus, MRP is based on four factors known to be
essential for the learning of motor skill and therefore assumed to be essential for the relearning
of motor control following stroke:
• The elimination of unnecessary muscle activity
• Feedback
• Practice
• Interrelationship between postural adjustment and movement
The research studies have indicated that all of the available approaches appear to promote
improvement in functional ability. A better theoretical understanding of the deficits In author’s
view, a treatment program consisting of mainly three components may be useful:
I. Traditional techniques of exercise therapy
II. The specific treatment approaches
III. Function-based techniques
Passive movements: In a recent study, it has been demonstrated that passive elbow movements
in hemiplegic stroke patients before clinical recovery elicit some of the brain activation
patterns described during active movement after substantial motor recovery.4 This indicates
that the recruitment of ipsilateral sensory and motor pathways early after stroke may be
critical for return of voluntary control. Therefore, it is recommended that patient should be
involved actively while performing passive movements in the early stage after stroke. He
must be instructed to pay attention towards the position of joints, stability of proximal parts,
movement of distal parts and the segmental alignment
In the recovery stage, passive movements are performed to get complete elongation of the
shortened muscle groups. The pattern of elongation for an upper extremity is scapular protraction
and upward rotation, shoulder lateral rotation and abduction, elbow extension, forearm supination, and wrist and finger extension. According to Odeen, the elongation of the shortened muscle groups at the point of maximally tolerated muscle length results in the reduction of hypertonicity.
Active movements: Patient should be encouraged to do the movements actively or better
said voluntarily, as soon as the muscle function begins to return. However, it must be kept
in mind that in hemiplegia, the return in muscle function is usually accompanied by the
emergence of synergistic movement patterns. Sahrmann and Norton have demonstrated
that as voluntary function increases, the dependence on synergistic movement decreases.
This suggests that the patient must be encouraged to produce the movements voluntarily.
Physical therapist may use her voice or touch to stimulate the patient’s voluntary effort so
as to produce the movements in the more normal patterns.
Functional stretching: This is the process of elongation of the shortened muscle groups
through weight-bearing . In hemiplegia, “Functional stretching” rather than
“orthopedic stretching” is more effective to improve range of motion.
Mobilization exercise: Joint dysfunction of the shoulder, scapula, hand, fingers, ankle and
forefoot may result as the secondary problem in hemiplegic patients. Mobilizing the scapula
is particularly important to improve the mobility of arm at shoulder and also to prevent
shoulder pain. This may be carried out in supine or side lying.
Progressive resisted exercise: Weakness from stroke differs from generalized weakness and
orthopedic weakness: it involves one entire side of the body and includes the trunk and
extremities.46 Traditionally, progressive resisted exercise was believed to cause a marked
loss of coordination and an increase in co-contraction. Therefore, this exercise was avoided
to the patients post-stroke. However, the latest studies have reported that patients with
hypertonicity may get benefit from progressive resisted exercise.
Aerobic exercise: Aerobic exercise is advised to patients of hemiplegia to improve the functional status. The research studies have indicated that aerobic exercise has the potential to develop the overall sensorimotor function after stroke.8 Walking on a treadmill, in particular, has
produced impressive positive findings in terms of independent walking.
Functional activities: The functional approach is well accepted by the patient. It makes the
treatment more meaningful. It includes task-specific activities such as
– Rolling
– Sitting control
– Sit to stand
– Standing control
– Transfers
– Gait
– Reaching activities
Gait training: In hemiplegic gait, there is disordered frequency, or phase relationship, between
pelvic and thoracic rotation and arm and leg movements. This may be due to a lack of
timing within coordination patterns and the general inability to switch between coordination
patterns.1 The training of essential components of walking can be started in early stage.
Examples of some of the activities are as following.
– Stimulating planter aspect of foot in supine lying. This may facilitate dorsiflexion of
foot.
– Extending hip with knee flexion over the side of the bed. This may prepare the
affected leg for the start of swing phase.
– Controlling hip movement while flexing the knee keeping ankle in dorsiflexion on affected
side, in the position of supine lying. This may prepare the affected leg for swing phase.
– Controlling knee flexors both eccentrically and concentrically throughout a small range
in prone lying. This may train flexion of affected knee at start of swing phase.
– Pelvis bridging in supine lying. This may facilitate extension of both hips.
– Pelvis bridging on affected leg. This may facilitate extension of affected hip.
– Weight transfer from side to side in sitting. This may facilitate balance reactions.
– Training the quadriceps for eccentric and concentric activity in sitting
– Standing with arms in extension held by therapist. This may facilitate extension of affected
hip.
– Stepping forward and backward with normal leg, keeping affected hip and knee in extension. This may facilitate weight bearing and balancing on affected leg.
– Stepping up and down with normal leg
– Shifting body weight from one foot to another in standing. This may facilitate training of
lateral horizontal pelvic shift
– Practicing controlled knee flexion in standing. This may train flexion of affected knee at
start of swing phase.
– Shifting body weight forward so as to put heel down while therapist holds the affected
foot in dorsiflexion with knee in extension. This may prepare the patient for heel strike.
– Bearing weight on affected leg. This may facilitate balance reactions.
– Rotating pelvis while walking. This may facilitate lateral rotation of both legs, in addition
to improving balance and walking pattern.
– Walking sideways
– Walking sideways while crossing the legs.
– Improving walking velocity. This may cause positive influence on the disordered

coordination patterns in trunk rotation and arm and leg movements.

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