Antiamoebic drugs


Classification of anti-amoebic drugs:

[A]Luminal/Intestinal:

1)      Diloxanite furoate.
2)      Iodoquinol.
3)      Antibiotic:
·         Tetracycline.
·         Erythromicin.
·         Paromomycin.


[B]Extra-luminal or Tissue amoebicides:

1)      Nitro-imidazole group:
·         Metronidazole.
·         Tinidazole.
·         Nidazole.
2)      Chloroqurine.
3)      Emetence:
·         Emetine hydrochloride.
·         Dehydroemetine.

Drugs of choice:

Clinical setting
Drugs
1.Asymptomatic intestine infection.
Diloxanite furoate

2.Mild to moderate intestinal infection (Ulcer is formed)
Metronidazole+Diloxanite furoate
3.Sever intestinal infection
Metronidazole+Diloxanite furoate
4.Liver absecess
Metronidazole+Diloxanite furoate

(Ref:Katzung-11th,P-913)

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